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matlab-based tool for the modeling and simulation of mpbpk models  (MathWorks Inc)


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    Structured Review

    MathWorks Inc matlab-based tool for the modeling and simulation of mpbpk models
    The minimal physiologically‐based pharmacokinetic ( <t>mPBPK</t> ) models that are used in ATLAS mPBPK. ( a ) mPBPK model for small molecules. ( b ) mPBPK model for large molecules with no target binding. ( c ) mPBPK model for large molecules with target binding in plasma (interstitial fluid). ( d ) mPBPK model for large molecules with target binding in peripheral tissues. Parameters' names and typical values are shown in Table . EV, extravascular; IV, intravenous; PO, oral.
    Matlab Based Tool For The Modeling And Simulation Of Mpbpk Models, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/matlab-based+tool+for+the+modeling+and+simulation+of+mpbpk+models/pmc06709424-123-14-6?v=MathWorks+Inc
    Average 90 stars, based on 1 article reviews
    matlab-based tool for the modeling and simulation of mpbpk models - by Bioz Stars, 2026-07
    90/100 stars

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    1) Product Images from "ATLAS mPBPK: A MATLAB‐Based Tool for Modeling and Simulation of Minimal Physiologically‐Based Pharmacokinetic Models"

    Article Title: ATLAS mPBPK: A MATLAB‐Based Tool for Modeling and Simulation of Minimal Physiologically‐Based Pharmacokinetic Models

    Journal: CPT: Pharmacometrics & Systems Pharmacology

    doi: 10.1002/psp4.12441

    The minimal physiologically‐based pharmacokinetic ( mPBPK ) models that are used in ATLAS mPBPK. ( a ) mPBPK model for small molecules. ( b ) mPBPK model for large molecules with no target binding. ( c ) mPBPK model for large molecules with target binding in plasma (interstitial fluid). ( d ) mPBPK model for large molecules with target binding in peripheral tissues. Parameters' names and typical values are shown in Table . EV, extravascular; IV, intravenous; PO, oral.
    Figure Legend Snippet: The minimal physiologically‐based pharmacokinetic ( mPBPK ) models that are used in ATLAS mPBPK. ( a ) mPBPK model for small molecules. ( b ) mPBPK model for large molecules with no target binding. ( c ) mPBPK model for large molecules with target binding in plasma (interstitial fluid). ( d ) mPBPK model for large molecules with target binding in peripheral tissues. Parameters' names and typical values are shown in Table . EV, extravascular; IV, intravenous; PO, oral.

    Techniques Used: Binding Assay, Clinical Proteomics

    Concordance of simulated ATLAS mPBPK small‐molecule model values based on pharmacokinetic data of beta‐lactams. Figure is not an output of ATLAS mPBPK but was constructed by processing ATLAS mPBPK simulation output using MATLAB.
    Figure Legend Snippet: Concordance of simulated ATLAS mPBPK small‐molecule model values based on pharmacokinetic data of beta‐lactams. Figure is not an output of ATLAS mPBPK but was constructed by processing ATLAS mPBPK simulation output using MATLAB.

    Techniques Used: Construct

    Demonstration of ATLAS mPBPK large‐molecule model based on PK data of Trastuzumab (target binding in peripheral tissues) and Mavrillimumab (target binding in plasma) for a range of doses. Figures are not an output of ATLAS mPBPK but were constructed by processing ATLAS mPBPK simulation output using MATLAB. c‐TMDD, Target mediated drug disposition in plasma (central); hr, hour; mPBPK, minimal physiologically‐based pharmacokinetic modeling; p‐TMDD, target‐mediated drug disposition in peripheral tissues.
    Figure Legend Snippet: Demonstration of ATLAS mPBPK large‐molecule model based on PK data of Trastuzumab (target binding in peripheral tissues) and Mavrillimumab (target binding in plasma) for a range of doses. Figures are not an output of ATLAS mPBPK but were constructed by processing ATLAS mPBPK simulation output using MATLAB. c‐TMDD, Target mediated drug disposition in plasma (central); hr, hour; mPBPK, minimal physiologically‐based pharmacokinetic modeling; p‐TMDD, target‐mediated drug disposition in peripheral tissues.

    Techniques Used: Binding Assay, Clinical Proteomics, Construct



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    matlab-based tool for the modeling and simulation of mpbpk models  (MathWorks Inc)
    90
    MathWorks Inc matlab-based tool for the modeling and simulation of mpbpk models
    The minimal physiologically‐based pharmacokinetic ( <t>mPBPK</t> ) models that are used in ATLAS mPBPK. ( a ) mPBPK model for small molecules. ( b ) mPBPK model for large molecules with no target binding. ( c ) mPBPK model for large molecules with target binding in plasma (interstitial fluid). ( d ) mPBPK model for large molecules with target binding in peripheral tissues. Parameters' names and typical values are shown in Table . EV, extravascular; IV, intravenous; PO, oral.
    Matlab Based Tool For The Modeling And Simulation Of Mpbpk Models, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/matlab-based+tool+for+the+modeling+and+simulation+of+mpbpk+models/pmc06709424-123-14-6?v=MathWorks+Inc
    Average 90 stars, based on 1 article reviews
    matlab-based tool for the modeling and simulation of mpbpk models - by Bioz Stars, 2026-07
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    The minimal physiologically‐based pharmacokinetic ( mPBPK ) models that are used in ATLAS mPBPK. ( a ) mPBPK model for small molecules. ( b ) mPBPK model for large molecules with no target binding. ( c ) mPBPK model for large molecules with target binding in plasma (interstitial fluid). ( d ) mPBPK model for large molecules with target binding in peripheral tissues. Parameters' names and typical values are shown in Table . EV, extravascular; IV, intravenous; PO, oral.

    Journal: CPT: Pharmacometrics & Systems Pharmacology

    Article Title: ATLAS mPBPK: A MATLAB‐Based Tool for Modeling and Simulation of Minimal Physiologically‐Based Pharmacokinetic Models

    doi: 10.1002/psp4.12441

    Figure Lengend Snippet: The minimal physiologically‐based pharmacokinetic ( mPBPK ) models that are used in ATLAS mPBPK. ( a ) mPBPK model for small molecules. ( b ) mPBPK model for large molecules with no target binding. ( c ) mPBPK model for large molecules with target binding in plasma (interstitial fluid). ( d ) mPBPK model for large molecules with target binding in peripheral tissues. Parameters' names and typical values are shown in Table . EV, extravascular; IV, intravenous; PO, oral.

    Article Snippet: In this tutorial, we present a MATLAB‐based tool for the modeling and simulation of mPBPK models (ATLAS mPBPK).

    Techniques: Binding Assay, Clinical Proteomics

    Concordance of simulated ATLAS mPBPK small‐molecule model values based on pharmacokinetic data of beta‐lactams. Figure is not an output of ATLAS mPBPK but was constructed by processing ATLAS mPBPK simulation output using MATLAB.

    Journal: CPT: Pharmacometrics & Systems Pharmacology

    Article Title: ATLAS mPBPK: A MATLAB‐Based Tool for Modeling and Simulation of Minimal Physiologically‐Based Pharmacokinetic Models

    doi: 10.1002/psp4.12441

    Figure Lengend Snippet: Concordance of simulated ATLAS mPBPK small‐molecule model values based on pharmacokinetic data of beta‐lactams. Figure is not an output of ATLAS mPBPK but was constructed by processing ATLAS mPBPK simulation output using MATLAB.

    Article Snippet: In this tutorial, we present a MATLAB‐based tool for the modeling and simulation of mPBPK models (ATLAS mPBPK).

    Techniques: Construct

    Demonstration of ATLAS mPBPK large‐molecule model based on PK data of Trastuzumab (target binding in peripheral tissues) and Mavrillimumab (target binding in plasma) for a range of doses. Figures are not an output of ATLAS mPBPK but were constructed by processing ATLAS mPBPK simulation output using MATLAB. c‐TMDD, Target mediated drug disposition in plasma (central); hr, hour; mPBPK, minimal physiologically‐based pharmacokinetic modeling; p‐TMDD, target‐mediated drug disposition in peripheral tissues.

    Journal: CPT: Pharmacometrics & Systems Pharmacology

    Article Title: ATLAS mPBPK: A MATLAB‐Based Tool for Modeling and Simulation of Minimal Physiologically‐Based Pharmacokinetic Models

    doi: 10.1002/psp4.12441

    Figure Lengend Snippet: Demonstration of ATLAS mPBPK large‐molecule model based on PK data of Trastuzumab (target binding in peripheral tissues) and Mavrillimumab (target binding in plasma) for a range of doses. Figures are not an output of ATLAS mPBPK but were constructed by processing ATLAS mPBPK simulation output using MATLAB. c‐TMDD, Target mediated drug disposition in plasma (central); hr, hour; mPBPK, minimal physiologically‐based pharmacokinetic modeling; p‐TMDD, target‐mediated drug disposition in peripheral tissues.

    Article Snippet: In this tutorial, we present a MATLAB‐based tool for the modeling and simulation of mPBPK models (ATLAS mPBPK).

    Techniques: Binding Assay, Clinical Proteomics, Construct